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RT Book, Whole SR Print DC OPAC T1 Wnt signaling : methods and protocols / edited by Quinn Barrett, University of Texas Southwestern Medical Center, Dallas, TX, USA, Lawrence Lum, Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA T2 Methods in molecular biology T2 Springer protocols A1 Barrett, Quinn A1 Lum, Lawrence YR 2016 FD [2016] SP xi, 198 pages K1 Wnt proteins -- Laboratory manuals K1 Wnt Signaling Pathway. https://id.nlm.nih.gov/mesh/D060449 K1 Wnt Proteins -- metabolism. https://id.nlm.nih.gov/mesh/D051153Q000378 K1 Signal Transduction -- physiology. https://id.nlm.nih.gov/mesh/D015398Q000502 K1 Laboratory Manuals. https://id.nlm.nih.gov/mesh/D020484 K1 Wnt proteins. fast (OCoLC)fst01176458 K1 Laboratory manuals. fast (OCoLC)fst01920776 PB Humana Press PP New York SN 9781493963911 SN 1493963910 LA English (英語) CL LCC:QP552.W58 CL NLM:W1 CL NLM:QU 25 NO Includes bibliographical references and index NO Summary: "Now poised to evaluate the potential in modulating Wnt signaling for therapeutic agendas in cancer, wound healing, and degenerative disease, this book collects protocols from an exciting area of study. The methodologies include using Wnt modulating chemicals in engineering tissues from induced pluripotent and embryonic stem cells, monitoring Wnt transcriptional responses in diverse tissues such as bone and skin, and using specific biochemical markers of Wnt signaling to either screen molecular libraries or evaluate novel reagents. These protocols also leverage unique experimental strengths from five different model organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Wnt Signaling: Methods and Protocols aims to support r NO HTTP:URL=http://www.loc.gov/catdir/enhancements/fy1616/2016942570-t.html Information=Table of contents NO HTTP:URL=http://catdir.loc.gov/catdir/enhancements/fy1616/2016942570-t.html Information=Table of contents NO HTTP:URL=http://www.springerprotocols.com/BookToc/doi/10.1007/978-1-4939-6393-5 Nonpub. note=purchased Pub. note=Available to Stanford-affiliated users at: NO HTTP:URL=https://link.springer.com/book/10.1007/978-1-4939-6393-5 NO 書誌ID=4000094754; NCID=GB96555823; LK [OPAC]https://www.lib.ntu.ac.jp/opac/opac_link/bibid/4000094754 OL 30